Gene Information gene info

  1. Home

GENE：SUPT5H

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SUPT5H
FullNmae SPT5 homolog, DSIF elongation factor subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11469
EnsembleID ENSG00000196235
Uniprot O00267

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SUPT5H autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SUPT5H autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SUPT5H GO:0000122,GO:0000122,GO:0003682,GO:0003723,GO:0003729,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006368,GO:0006368,GO:0006368,GO:0016239,GO:0019899,GO:0032044,GO:0032044,GO:0032044,GO:0032785,GO:0032785,GO:0032786,GO:0034243,GO:0045944,GO:0046982,GO:0140673

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SUPT5H hsa:6829 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUPT5H TNFAIP3 17962196 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUPT5H USF1 17962196 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SUPT5H 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SUPT5H 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SUPT5H 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SUPT5H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SUPT5H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SUPT5H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SUPT5H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SUPT5H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SUPT5H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC SUPT5H N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 SUPT5H 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EED18 SUPT5H 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 SUPT5H 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000033EBB8 SUPT5H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 SUPT5H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 SUPT5H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SUPT5H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D SUPT5H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D SUPT5H 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 SUPT5H 22135298 phosphorylation N/A PhosphoSite
CDK2 SUPT5H 22135298 phosphorylation N/A PhosphoSite
CDK9 SUPT5H 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SUPT5H POLR2F 25361965 interaction type N/A PTMCode2
POLR2F SUPT5H 25361965 interaction type N/A PTMCode2
HTATSF1 SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H HTATSF1 25361965 interaction type N/A PTMCode2
PIN1 SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H PIN1 25361965 interaction type N/A PTMCode2
SSRP1 SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H SSRP1 25361965 interaction type N/A PTMCode2
SUPT4H1 SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H SUPT4H1 25361965 interaction type N/A PTMCode2
CCNH SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H CCNH 25361965 interaction type N/A PTMCode2
POLR2B SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H POLR2B 25361965 interaction type N/A PTMCode2
POLR2C SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H POLR2C 25361965 interaction type N/A PTMCode2
SUPT16H SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H SUPT16H 25361965 interaction type N/A PTMCode2
POLR2G SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H POLR2G 25361965 interaction type N/A PTMCode2
SUPT5H CDK9 25361965 interaction type N/A PTMCode2
CDK7 SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H CDK7 25361965 interaction type N/A PTMCode2
SUPT5H RTF1 25361965 interaction type N/A PTMCode2
RTF1 SUPT5H 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 SUPT5H 11575923 14525934 21988832 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct
HNRNPK SUPT5H 25348397 N/A physical interaction ComPPI
GOLGA2 SUPT5H 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
CCNH SUPT5H 25348397 N/A physical interaction ComPPI
CDC73 SUPT5H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP30BP SUPT5H 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
POLR2L SUPT5H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZFYVE9 SUPT5H 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CEP43 SUPT5H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LCA5 SUPT5H 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SET SUPT5H 25348397 N/A physical interaction ComPPI
LMNA SUPT5H 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PCBD1 SUPT5H 25348397 N/A physical interaction ComPPI
ZNF512B SUPT5H 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KHDRBS2 SUPT5H 25348397 N/A physical interaction ComPPI
PAK5 SUPT5H 25348397 N/A physical interaction ComPPI
SWAP70 SUPT5H 25348397 N/A physical interaction ComPPI
PPP4C SUPT5H 25348397 N/A physical interaction ComPPI
GTF2F2 SUPT5H 25348397 N/A physical interaction ComPPI
NELFB SUPT5H 25348397 N/A physical interaction ComPPI
CPNE2 SUPT5H 25348397 N/A physical interaction ComPPI
CPNE4 SUPT5H 25348397 N/A physical interaction ComPPI
CUL3 SUPT5H 25348397 N/A physical interaction ComPPI
MCM10 SUPT5H 25348397 N/A physical interaction ComPPI
HSP90AA1 SUPT5H 25348397 N/A physical interaction ComPPI
NTRK1 SUPT5H 25348397 N/A physical interaction ComPPI
ENO1 SUPT5H 25348397 N/A physical interaction ComPPI
PRMT1 SUPT5H 12718890 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TNS2 SUPT5H 25348397 N/A physical interaction ComPPI
XRCC5 SUPT5H 12391174 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SUB1 SUPT5H 22973055 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MSH6 SUPT5H 25348397 N/A physical interaction ComPPI
CSNK2A1 SUPT5H 25348397 N/A physical interaction,protein kinase assay ComPPI
XRCC6 SUPT5H 25348397 N/A physical interaction ComPPI
PRMT5 SUPT5H 12718890 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
UBR5 SUPT5H 25348397 N/A physical interaction ComPPI
NFATC2 SUPT5H 25348397 N/A physical interaction ComPPI
CTR9 SUPT5H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MNAT1 SUPT5H 25348397 N/A physical interaction ComPPI
CCNT2 SUPT5H 25348397 N/A physical interaction ComPPI
RANGAP1 SUPT5H 25348397 N/A physical interaction ComPPI
HTATSF1 SUPT5H 10454543 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CSNK2A2 SUPT5H 25348397 N/A physical interaction ComPPI
PAPOLA SUPT5H 25348397 N/A physical interaction ComPPI
CEP55 SUPT5H 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
SOX2 SUPT5H 25348397 N/A physical interaction ComPPI
EGFR SUPT5H 25348397 N/A physical interaction ComPPI
HTT SUPT5H 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
RNF2 SUPT5H 25348397 N/A physical interaction ComPPI
TAF6 SUPT5H 25348397 N/A physical interaction ComPPI
NOLC1 SUPT5H 25348397 N/A physical interaction ComPPI
POLR2E SUPT5H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK7 SUPT5H 16327805 24234451 25348397 N/A physical interaction,protein kinase assay ComPPI,IntAct
POLR2A SUPT5H 10075709 10454543 11940650 14525934 18197258 21880767 22939629 24234451 24814348 25348397 25416956 26344197 26496610 27898060 9450929 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,far western blotting,physical interaction,mammalian protein protein interaction trap,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
CCNT1 SUPT5H 25348397 N/A physical interaction ComPPI
DOK4 SUPT5H 25348397 N/A physical interaction ComPPI
HSPB1 SUPT5H 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
MAML3 SUPT5H 25348397 N/A physical interaction ComPPI
SMC3 SUPT5H 25348397 N/A physical interaction ComPPI
SF1 SUPT5H 25348397 N/A physical interaction ComPPI
CEP126 SUPT5H 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PAK4 SUPT5H 25348397 N/A physical interaction ComPPI
JADE1 SUPT5H 25348397 N/A physical interaction ComPPI
MED14 SUPT5H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL7 SUPT5H 25348397 N/A physical interaction ComPPI
SUPT5H CDK9 11145967 11575923 14525934 16327805 24234451 25348397 N/A experimental interaction detection,physical interaction,protein kinase assay,in vitro ComPPI,HPRD,IntAct
SUPT5H SUPT4H1 10075709 10454543 12653964 12718890 14525934 17404243 19860741 22939629 24234451 25348397 25416956 26344197 26496610 26789250 27107012 27898060 association,physical association anti tag coimmunoprecipitation,cross-linking study,experimental interaction detection,far western blotting,molecular sieving,pull down,physical interaction,mammalian protein protein interaction trap,in vitro,split luciferase complementation,validated two hybrid,barcode fusion genetics two hybrid ComPPI,HPRD,IntAct,OmniPath
SUPT5H PPIA 14525934 16169070 24234451 25348397 physical association two hybrid,pull down,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUPT5H DBN1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUPT5H H2AX 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUPT5H PPP2R2D 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUPT5H C9ORF78 14525934 16169070 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SUPT5H PNO1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUPT5H PHYHIP 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUPT5H DCAF6 14525934 16169070 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SUPT5H GTF3C1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUPT5H IKBKG 25348397 N/A physical interaction ComPPI
SUPT5H SSBP3 25348397 N/A physical interaction ComPPI
SUPT5H ZBTB3 25348397 N/A physical interaction ComPPI
SUPT5H ZNF496 25348397 N/A physical interaction ComPPI
SUPT5H SIRT7 25348397 N/A physical interaction ComPPI
SUPT5H TERF1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
SUPT5H NENF 25348397 N/A physical interaction ComPPI
SUPT5H CDH2 25348397 N/A physical interaction ComPPI
SUPT5H PPT2 25348397 N/A physical interaction ComPPI
SUPT5H HSP90AA2P 25348397 N/A physical interaction ComPPI
SUPT5H BARD1 25348397 N/A physical interaction ComPPI
SUPT5H POLR2C 18562274 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
SUPT5H NSMF 25348397 N/A physical interaction ComPPI
SUPT5H SNX4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SUPT5H LMAN2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SUPT5H SIK1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SUPT5H CARM1 25348397 N/A physical interaction ComPPI
SUPT5H RANBP3 25348397 N/A physical interaction ComPPI
SUPT5H SEC24C 25348397 N/A physical interaction ComPPI
SUPT5H CSDE1 25348397 N/A physical interaction ComPPI
SUPT5H FARSB 25348397 N/A physical interaction ComPPI
SUPT5H GANAB 25348397 N/A physical interaction ComPPI
SUPT5H GART 25348397 N/A physical interaction ComPPI
SUPT5H MSH2 25348397 N/A physical interaction ComPPI
SUPT5H PAICS 25348397 N/A physical interaction ComPPI
SUPT5H PLOD2 25348397 N/A physical interaction ComPPI
SUPT5H SAMHD1 25348397 N/A physical interaction ComPPI
SUPT5H BRCA1 25348397 N/A physical interaction ComPPI
SUPT5H SHMT2 25348397 N/A physical interaction ComPPI
SUPT5H MOV10 25348397 N/A physical interaction ComPPI
SUPT5H NXF1 25348397 N/A physical interaction ComPPI
SUPT5H OBSL1 25348397 N/A physical interaction ComPPI
SUPT5H SIRT6 25348397 N/A physical interaction ComPPI
SUPT5H VPS26B 25348397 N/A physical interaction ComPPI
SUPT5H CDKL1 25348397 N/A physical interaction ComPPI
SUPT5H CSNK2B 25348397 N/A physical interaction ComPPI
SUPT5H PAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H POLR2B 25348397 N/A physical interaction ComPPI
SUPT5H CPSF2 25348397 N/A physical interaction ComPPI
SUPT5H MRTO4 25348397 N/A physical interaction ComPPI
SUPT5H NCL 25348397 N/A physical interaction ComPPI
SUPT5H POLR2F 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H POLR2H 25348397 N/A physical interaction ComPPI
SUPT5H RTF1 11927560 22796944 23775116 24101474 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SUPT5H SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H IFI16 25348397 N/A physical interaction ComPPI
SUPT5H CEP290 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H OFD1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H PCM1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H POLR2D 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H POLR2G 23418395 24234451 24358479 24513203 24813444 25348397 26496610 27898060 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
SUPT5H POLR2I 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H FAN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H NCBP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H IWS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H NELFA 12612062 24234451 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SUPT5H WIPF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H SETX 25348397 N/A physical interaction ComPPI
SUPT5H SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H RPRD2 25348397 N/A physical interaction ComPPI
SUPT5H PHF3 25348397 N/A physical interaction ComPPI
SUPT5H POC1A 25348397 N/A physical interaction ComPPI
SUPT5H RPRD1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H WDR61 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H RNF214 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H EYA4 25348397 N/A physical interaction ComPPI
SUPT5H RNGTT 25348397 N/A physical interaction ComPPI
SUPT5H PLEKHO1 25348397 N/A physical interaction ComPPI
SUPT5H CPNE7 25348397 N/A physical interaction ComPPI
SUPT5H AIPL1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
SUPT5H MIOS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SUPT5H PDE5A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SUPT5H TRIM25 25348397 N/A physical interaction ComPPI
SUPT5H MED31 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SUPT5H RPL8 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SUPT5H PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
SUPT5H CEP170P1 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
SUPT5H MAD1L1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
HNRNPF SUPT5H 25348397 N/A physical interaction ComPPI
ILF2 SUPT5H 25348397 N/A physical interaction ComPPI
POLR2J SUPT5H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EEF1D SUPT5H 25348397 N/A physical interaction ComPPI
IK SUPT5H 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LEO1 SUPT5H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6V1B2 SUPT5H 25348397 N/A physical interaction ComPPI
SUPT5H SUPT5H 10199401 11112772 11940650 14525934 N/A experimental interaction detection HPRD
SUPT5H ANKRD37 23746844 24234451 association chromatin immunoprecipitation assay IntAct
OCIAD2 SUPT5H 24234451 30021884 physical association cross-linking study IntAct
SUPT5H USF1 17962196 27898060 N/A N/A OmniPath
SUPT5H NRDC 16427013 21949810 24324601 27898060 N/A N/A OmniPath
CDK9 SUPT5H 10757782 10958691 11145967 11575923 15201869 16327805 16427012 23064645 27898060 stimulant N/A OmniPath
PRMT1 SUPT5H 12718890 27898060 N/A N/A OmniPath
PRMT5 SUPT5H 12718890 15670829 27898060 N/A N/A OmniPath

Visualization










  Return