GENE:TBC1D14
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TBC1D14 |
| FullNmae | TBC1 domain family member 14 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29246 |
| EnsembleID | ENSG00000132405 |
| Uniprot | Q9P2M4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TBC1D14 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TBC1D14 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TBC1D14 | GO:0005096,GO:0005515,GO:0005654,GO:0005776,GO:0005776,GO:0005794,GO:0005829,GO:0006914,GO:0010507,GO:0019901,GO:0043231,GO:0055037,GO:0055037,GO:0055037,GO:0071955,GO:0090630,GO:2000785,GO:2000785 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TBC1D14 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | TBC1D14 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | TBC1D14 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | TBC1D14 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TBC1D14 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | TBC1D14 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | TBC1D14 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| NR1I2 | TBC1D14 | 19129222 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | TBC1D14 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | TBC1D14 | 20584899 | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS0000338542 | TBC1D14 | 20584899 22473208 25416803 | mrna cleavage,inhibition | experimental interaction detection,clip | TarBase |
| URS00003CF1AD | TBC1D14 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000040EE1D | TBC1D14 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | TBC1D14 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | TBC1D14 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | TBC1D14 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | TBC1D14 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F305A | TBC1D14 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TFRC | TBC1D14 | 22613832 24234451 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| HNRNPL | TBC1D14 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | TBC1D14 | 25348397 | N/A | physical interaction | ComPPI |
| GRK2 | TBC1D14 | 25348397 | N/A | physical interaction | ComPPI |
| RAB11A | TBC1D14 | 22613832 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| TFEB | TBC1D14 | 25348397 | N/A | physical interaction | ComPPI |
| RAB11FIP3 | TBC1D14 | 22613832 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| PML | TBC1D14 | 25348397 | N/A | physical interaction | ComPPI |
| ULK1 | TBC1D14 | 22613832 24234451 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy | ComPPI,IntAct |
| CENPA | TBC1D14 | 25348397 | N/A | physical interaction | ComPPI |
| TRAPPC2L | TBC1D14 | 25348397 | N/A | physical interaction | ComPPI |
| UBE3A | TBC1D14 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| NXF1 | TBC1D14 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ATG13 | TBC1D14 | 22613832 24234451 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| TBC1D14 | TRAPPC9 | 25348397 | N/A | physical interaction | ComPPI |
| EEF1G | TBC1D14 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| SPARC | TBC1D14 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| OCIAD2 | TBC1D14 | 24234451 30021884 | physical association | cross-linking study | IntAct |
