Gene Information gene info

GENE:TMEM59

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMEM59
FullNmae transmembrane protein 59
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1239
EnsembleID ENSG00000116209
Uniprot Q9BXS4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMEM59 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM59 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TMEM59 GO:0000137,GO:0000138,GO:0000139,GO:0004175,GO:0005515,GO:0005764,GO:0005764,GO:0005765,GO:0005770,GO:0005770,GO:0005797,GO:0005886,GO:0006486,GO:0006914,GO:0010508,GO:0010508,GO:0031902,GO:0070062,GO:1903077

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TMEM59 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TMEM59 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TMEM59 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TMEM59 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 TMEM59 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00001C770D TMEM59 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 TMEM59 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001E0AEA TMEM59 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 TMEM59 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D TMEM59 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 TMEM59 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D TMEM59 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F14FE TMEM59 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 TMEM59 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013D17D TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A122A TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001496AE TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 TMEM59 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ERRFI1 TMEM59 25348397 N/A physical interaction ComPPI
NTRK1 TMEM59 25348397 N/A physical interaction ComPPI
AP1M1 TMEM59 23376921 24234451 25348397 physical association pull down ComPPI,IntAct
PARP2 TMEM59 21812934 24234451 25348397 adp ribosylation reaction protein array ComPPI,IntAct
MAP1LC3A TMEM59 23376921 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
CUL7 TMEM59 25348397 N/A physical interaction ComPPI
AP2M1 TMEM59 23376921 24234451 25348397 physical association pull down ComPPI,IntAct
ELAVL1 TMEM59 25348397 N/A physical interaction ComPPI
IL20RB TMEM59 25348397 N/A physical interaction ComPPI
ATG16L1 TMEM59 23376921 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
RYK TMEM59 25348397 N/A physical interaction ComPPI
TMEM59 PDE3B 25348397 N/A physical interaction ComPPI
TMEM59 TMEM30A 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009AD46B TMEM59 27087310 direct interaction,inhibition N/A NPInter

Visualization