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GENE：VPS26A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VPS26A
FullNmae VPS26 retromer complex component A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12711
EnsembleID ENSG00000122958
Uniprot O75436

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VPS26A autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VPS26A autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
VPS26A GO:0005515,GO:0005764,GO:0005768,GO:0005768,GO:0005769,GO:0005829,GO:0006886,GO:0010008,GO:0016241,GO:0030904,GO:0030904,GO:0030904,GO:0030906,GO:0030906,GO:0031982,GO:0032456,GO:0042147,GO:0042147,GO:0042147,GO:0097422

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VPS26A hsa:9559 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 VPS26A 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 VPS26A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 VPS26A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VPS26A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 VPS26A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 VPS26A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS VPS26A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF VPS26A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 VPS26A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 VPS26A N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 VPS26A 15685193 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D VPS26A 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00002075FA VPS26A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F VPS26A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 VPS26A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 VPS26A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 VPS26A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 VPS26A 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NMI VPS26A 25348397 N/A physical interaction ComPPI
VPS4B VPS26A 25348397 N/A physical interaction ComPPI
ZNRD2 VPS26A 25348397 N/A physical interaction ComPPI
STAT1 VPS26A 25348397 N/A physical interaction ComPPI
KEAP1 VPS26A 25348397 N/A physical interaction ComPPI
MPDZ VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM4 VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB7A VPS26A 25348397 N/A physical interaction ComPPI
NTRK1 VPS26A 25348397 N/A physical interaction ComPPI
SNX1 VPS26A 11102511 24234451 25348397 association,physical association anti bait coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
SNX2 VPS26A 11102511 15078903 24234451 25348397 colocalization,physical association molecular sieving,physical interaction,confocal microscopy ComPPI,IntAct
BAG6 VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ILK VPS26A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HDLBP VPS26A 25348397 N/A physical interaction ComPPI
RUFY1 VPS26A 25348397 N/A physical interaction ComPPI
NAA10 VPS26A 25348397 N/A physical interaction ComPPI
H1-4 VPS26A 25348397 N/A physical interaction ComPPI
NOLC1 VPS26A 25348397 N/A physical interaction ComPPI
RAI14 VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNM1L VPS26A 25348397 N/A physical interaction ComPPI
FGB VPS26A 25348397 N/A physical interaction ComPPI
ETF1 VPS26A 25348397 N/A physical interaction ComPPI
NFKB1 VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3-3A VPS26A 25348397 N/A physical interaction ComPPI
SYMPK VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE4B VPS26A 25348397 N/A physical interaction ComPPI
ELAVL1 VPS26A 25348397 N/A physical interaction ComPPI
UBQLN1 VPS26A 25348397 N/A physical interaction ComPPI
VPS35 VPS26A 11102511 15078903 16732284 17891154 22863883 22939629 24234451 24344282 24747528 25348397 26186194 26344197 26496610 27898060 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,transmission electron microscopy,molecular sieving,pull down,physical interaction,two hybrid array,confocal microscopy,lexa b52 complementation,two hybrid prey pooling approach,thermal shift binding ComPPI,IntAct,OmniPath
NUDC VPS26A 25348397 N/A physical interaction ComPPI
UBE2V2 VPS26A 25348397 N/A physical interaction ComPPI
VPS29 VPS26A 11102511 16732284 17891154 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,transmission electron microscopy,molecular sieving,physical interaction ComPPI,IntAct
EHD1 VPS26A 25348397 N/A physical interaction ComPPI
MCM7 VPS26A 25348397 N/A physical interaction ComPPI
ERCC4 VPS26A 25348397 N/A physical interaction ComPPI
IGF2R VPS26A 15078903 24234451 25348397 colocalization electron microscopy,confocal microscopy ComPPI,IntAct
USP1 VPS26A 25348397 N/A physical interaction ComPPI
APEH VPS26A 25348397 N/A physical interaction ComPPI
ENTR1 VPS26A 25348397 N/A physical interaction ComPPI
CELF1 VPS26A 25348397 N/A physical interaction ComPPI
CPSF6 VPS26A 25348397 N/A physical interaction ComPPI
MIF VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TBC1D5 VPS26A 20923837 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SEC24A VPS26A 25348397 N/A physical interaction ComPPI
MUL1 VPS26A 25348397 N/A physical interaction ComPPI
PSMC2 VPS26A 25348397 N/A physical interaction ComPPI
CORO1B VPS26A 25348397 N/A physical interaction ComPPI
NAA15 VPS26A 25348397 N/A physical interaction ComPPI
TARS1 VPS26A 25348397 N/A physical interaction ComPPI
AHCYL1 VPS26A 25348397 N/A physical interaction ComPPI
FN1 VPS26A 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
CAPZB VPS26A 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
COX6B1 VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RYK VPS26A 25348397 N/A physical interaction ComPPI
H1-10 VPS26A 25348397 N/A physical interaction ComPPI
CORO1C VPS26A 25348397 N/A physical interaction ComPPI
ANKFY1 VPS26A 25348397 N/A physical interaction ComPPI
NIBAN2 VPS26A 25348397 N/A physical interaction ComPPI
PLEKHA7 VPS26A 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
RBM26 VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BHLHE41 VPS26A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JMJD6 VPS26A 25348397 N/A physical interaction ComPPI
VPS26A UBXN7 25348397 N/A physical interaction ComPPI
VPS26A RIOK2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
VPS26A UTP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS26A WASHC2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS26A DUSP8 25348397 N/A physical interaction ComPPI
RPL4 VPS26A 24234451 30021884 physical association cross-linking study IntAct

Visualization










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