GENE:VPS26B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | VPS26B |
| FullNmae | VPS26 retromer complex component B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:28119 |
| EnsembleID | ENSG00000151502 |
| Uniprot | Q4G0F5 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| VPS26B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| VPS26B | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| VPS26B | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| VPS26B | GO:0005515,GO:0005768,GO:0005769,GO:0005770,GO:0005829,GO:0006886,GO:0016241,GO:0030904,GO:0030904,GO:0030906,GO:0042147,GO:0042147,GO:0042147,GO:0045335,GO:0071346 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| VPS26B | hsa:112936 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | VPS26B | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA2 | VPS26B | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CTCF | VPS26B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | VPS26B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | VPS26B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | VPS26B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | VPS26B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F4AC3 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000013ABA3 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B341F | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000330617 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000017DBB8 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000939AF | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001EB3 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000037E170 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000250A40 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075ABF4 | VPS26B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TTF1 | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| COL4A5 | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NTRK1 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| ENO1 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| SNX1 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| SNX2 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| MYCBP2 | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NEK1 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| ETV6 | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SUPT5H | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| KIF1B | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VPS35 | VPS26B | 14525934 16190980 22939629 24234451 25348397 26186194 26344197 26496610 27898060 | association,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| MYH1 | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CAB39 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| VPS29 | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PPIL2 | VPS26B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ENTR1 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| TXNDC11 | VPS26B | 25348397 | N/A | physical interaction | ComPPI |
| TBC1D5 | VPS26B | 20923837 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VPS26B | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| VPS26B | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS26B | CFAP410 | 25348397 | N/A | physical interaction | ComPPI |
| VPS26B | SNX27 | 25348397 | N/A | physical interaction | ComPPI |
| VPS26B | MRM1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS26B | MRPS30 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VPS26B | CCDC102B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VPS26B | WASHC2A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
