Gene Information gene info

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GENE：WDR6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WDR6
FullNmae WD repeat domain 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12758
EnsembleID ENSG00000178252
Uniprot Q9NNW5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WDR6 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WDR6 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
WDR6 GO:0000049,GO:0002130,GO:0003723,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0008285,GO:0010507,GO:0030234,GO:0030488,GO:0070314

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELANE WDR6 19506020 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 WDR6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
NR1I2 WDR6 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF WDR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 WDR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 WDR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 WDR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WDR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F4AC3 WDR6 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS0000512C88 WDR6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000048BA36 WDR6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 WDR6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 WDR6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008F0CF WDR6 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 WDR6 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
WDR6 CDC42EP4 14525934 16189514 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
WDR6 G2E3 14525934 16189514 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
WDR6 SIRT7 25348397 N/A physical interaction ComPPI
WDR6 CUL3 25348397 N/A physical interaction ComPPI
WDR6 PPIP5K2 25348397 N/A physical interaction ComPPI
WDR6 MAP2K7 25348397 N/A physical interaction ComPPI
WDR6 TIA1 25348397 N/A physical interaction ComPPI
WDR6 BRCA1 25348397 N/A physical interaction ComPPI
WDR6 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
WDR6 GRB2 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR6 DYRK1B 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
WDR6 HIPK4 25348397 N/A physical interaction ComPPI
WDR6 ILK 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
WDR6 IRS4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR6 EMD 25348397 N/A physical interaction ComPPI
WDR6 PTPN3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
WDR6 EGFR 25348397 N/A physical interaction ComPPI
WDR6 STK11 17216128 24234451 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
WDR6 FTSJ1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR6 NTRK1 25348397 N/A physical interaction ComPPI
WDR6 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
WDR6 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
WDR6 CDC25B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR6 RNF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR6 RPL10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR6 CDC37 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR6 KMT2E 25348397 N/A physical interaction ComPPI
WDR6 MEX3C 25348397 N/A physical interaction ComPPI
WDR6 PAPSS2 25348397 N/A physical interaction ComPPI
WDR6 DMWD 25348397 N/A physical interaction ComPPI
WDR6 AMY1C 25348397 N/A physical interaction ComPPI
WDR6 JCHAIN 25348397 N/A physical interaction ComPPI
WDR6 TRIM25 25348397 N/A physical interaction ComPPI
WDR6 BRAF 25348397 N/A physical interaction ComPPI
WDR6 KEAP1 25348397 N/A physical interaction ComPPI
WDR6 COPS5 18850735 24234451 25348397 association tandem affinity purification ComPPI,IntAct
WDR6 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR6 ULK2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR6 MAPK6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR6 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR6 TUBA1A 24234451 25348397 27291054 association pull down ComPPI,IntAct
WDR6 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR6 KSR2 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR6 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
WDR6 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
WDR6 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
WDR6 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

Visualization










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