GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
WDR75 |
FullNmae |
WD repeat domain 75 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:25725 |
EnsembleID |
ENSG00000115368 |
Uniprot |
Q8IWA0 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
WDR75 |
autophagy |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
WDR75 |
GO:0003723,GO:0003723,GO:0005654,GO:0005730,GO:0005730,GO:0006364,GO:0032040,GO:0042274,GO:0045943,GO:0045943,GO:2000234,GO:2000234 |
KEGG Annotation:
GeneSymbol |
GeneID |
Pathway |
Pathway Name |
WDR75 |
hsa:84128 |
path:hsa03008 |
Ribosome biogenesis in eukaryotes - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
WDR75 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
ETS1 |
WDR75 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
GATA2 |
WDR75 |
18971253
19941826
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
WDR75 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
WDR75 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F1 |
WDR75 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
WDR75 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
WDR75 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
WDR75 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
RUNX1 |
WDR75 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000065D58 |
WDR75 |
18668040
25416803
|
mrna cleavage,inhibition |
experimental interaction detection |
TarBase |
URS0000324096 |
WDR75 |
18668040
25416803
|
mrna cleavage,inhibition |
experimental interaction detection |
TarBase |
URS000040FA88 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075C1E1 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002A8BC6 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000032AE90 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003E5ECC |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000100748 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075A760 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002152A8 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000137EDE |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000019907A |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002B0B46 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000076E54 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001C770D |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000C5969 |
WDR75 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
EXOSC5 |
WDR75 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
CIAO1 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
RBM4 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
CDH5 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
CHM |
WDR75 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
ATP6AP2 |
WDR75 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
CUL7 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
FOXA1 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
RAE1 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
IFI16 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
RRP1B |
WDR75 |
20926688
24234451
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
PLEK |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
FBL |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
SIRT7 |
WDR75 |
25348397
|
N/A |
physical interaction |
ComPPI |
WDR75 |
OBSL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
WDR75 |
FAN1 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
WDR75 |
UTP4 |
22916032
24234451
25348397
|
association |
physical interaction,tandem affinity purification |
ComPPI,IntAct |
WDR75 |
NOL7 |
25348397
|
N/A |
physical interaction |
ComPPI |
WDR75 |
ASB7 |
25348397
|
N/A |
physical interaction |
ComPPI |
WDR75 |
WDFY3 |
25348397
|
N/A |
physical interaction |
ComPPI |
WDR75 |
CACNB1 |
25348397
|
N/A |
physical interaction |
ComPPI |
WDR75 |
MCPH1 |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization