GENE:ATG10
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ATG10 |
| FullNmae | autophagy related 10 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20315 |
| EnsembleID | ENSG00000152348 |
| Uniprot | Q9H0Y0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ATG10 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ATG10 | GO:0000045,GO:0005515,GO:0005829,GO:0006497,GO:0006497,GO:0006914,GO:0006983,GO:0015031,GO:0016236,GO:0019777,GO:0019777,GO:0031401,GO:0032446,GO:0032446,GO:0061651 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ATG10 | hsa:83734 | path:hsa04136 | Autophagy - other - Homo sapiens (human) |
| ATG10 | hsa:83734 | path:hsa04140 | Autophagy - animal - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ATG10 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | ATG10 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | ATG10 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | ATG10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F31F4 | ATG10 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | ATG10 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000148B91 | ATG10 | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000046CDA6 | ATG10 | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | ATG10 | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000061E50F | ATG10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | ATG10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | ATG10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013E79D | ATG10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | ATG10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | ATG10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | ATG10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HAT1 | ATG10 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GABARAPL2 | ATG10 | 20562859 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| MAP1LC3B | ATG10 | 20562859 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| USP7 | ATG10 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GABARAP | ATG10 | 20562859 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| USP11 | ATG10 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ATG3 | ATG10 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ATG7 | ATG10 | 12482611 14525934 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| ATG12 | ATG10 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction,in vitro,in vivo | ComPPI,IntAct |
| ATG10 | KRT85 | 25348397 | N/A | physical interaction | ComPPI |
| ATG10 | MAP1B | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ATG10 | ATG4B | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ATG10 | RBBP7 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ATG10 | ADSS2 | 25348397 | N/A | physical interaction | ComPPI |
| ATG10 | GABARAPL1 | 20562859 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| ATG10 | MAP1LC3C | 20562859 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| ATG10 | MAP1LC3B2 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ATG10 | ATG5 | 12482611 14525934 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ATG10 | ATG10 | 20562859 24234451 | physical association | anti tag coimmunoprecipitation | IntAct |
| ATG7 | ATG10 | 10508157 11096062 11890701 12482611 20562859 22056771 23142976 26186194 27898060 9759731 | stimulant | N/A | OmniPath |
| TP63 | ATG10 | 22356768 27898060 | N/A | N/A | OmniPath |
| SOX2 | ATG10 | 23451179 27898060 | N/A | N/A | OmniPath |
| ATG12 | ATG10 | 10508157 12482611 16963840 17353931 26186194 27898060 | N/A | N/A | OmniPath |
| ATG10 | ATG12 | 10508157 11265251 12482611 16963840 17353931 18704115 26186194 27898060 | stimulant | N/A | OmniPath |
| ATG10 | ATG5 | 10508157 12482611 16963840 27898060 | stimulant | N/A | OmniPath |
