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GENE：DYNC1I1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DYNC1I1
FullNmae dynein cytoplasmic 1 intermediate chain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2963
EnsembleID ENSG00000158560
Uniprot O14576

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DYNC1I1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DYNC1I1 GO:0000776,GO:0000922,GO:0003774,GO:0003777,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005868,GO:0005868,GO:0005874,GO:0008017,GO:0010970,GO:0030507,GO:0031982,GO:0036464,GO:0045503,GO:0045504,GO:0047496,GO:0047496,GO:0048471,GO:0055037

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DYNC1I1 hsa:1780 path:hsa04145 Phagosome - Homo sapiens (human)
DYNC1I1 hsa:1780 path:hsa04814 Motor proteins - Homo sapiens (human)
DYNC1I1 hsa:1780 path:hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human)
DYNC1I1 hsa:1780 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DYNC1I1 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
BICD1 DYNC1I1 17139249 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR DYNC1I1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 DYNC1I1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DYNC1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 DYNC1I1 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FAM110A DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DYNLL1 DYNC1I1 11148209 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
FBP1 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DYNLL2 DYNC1I1 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CDKN1A DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DYNC2I2 DYNC1I1 25348397 N/A physical interaction ComPPI
TK1 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMN1 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GRB7 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD2 DYNC1I1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
EP300 DYNC1I1 25348397 N/A physical interaction ComPPI
CUL3 DYNC1I1 25348397 N/A physical interaction ComPPI
DYNC1LI1 DYNC1I1 25348397 N/A physical interaction ComPPI
DYNLT3 DYNC1I1 25348397 N/A physical interaction ComPPI
KCNA5 DYNC1I1 25348397 N/A physical interaction ComPPI
NAGK DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DCTN1 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BICD2 DYNC1I1 25348397 N/A physical interaction ComPPI
RCC1 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAFAH1B1 DYNC1I1 25348397 N/A physical interaction ComPPI
KAT7 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BECN1 DYNC1I1 25348397 N/A physical interaction ComPPI
DYNC1H1 DYNC1I1 25348397 N/A physical interaction ComPPI
RAP1GAP DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DYNLT1 DYNC1I1 14525934 25348397 27898060 8943288 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
KLC3 DYNC1I1 25348397 N/A physical interaction ComPPI
NDEL1 DYNC1I1 19927128 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL23 DYNC1I1 25348397 N/A physical interaction ComPPI
TAOK1 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DCTN2 DYNC1I1 25348397 N/A physical interaction ComPPI
DYNC1I2 DYNC1I1 25348397 N/A physical interaction ComPPI
ZW10 DYNC1I1 15824131 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
TUBB1 DYNC1I1 16616141 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DYNLRB1 DYNC1I1 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCC DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EMILIN1 DYNC1I1 25348397 N/A physical interaction ComPPI
TUBB3 DYNC1I1 25348397 N/A physical interaction ComPPI
C15ORF39 DYNC1I1 25348397 N/A physical interaction ComPPI
WDCP DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CADM4 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AMBRA1 DYNC1I1 25348397 N/A physical interaction ComPPI
MC1R DYNC1I1 25348397 N/A physical interaction ComPPI
TP53 DYNC1I1 16616141 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DNM2 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DISC1 DYNC1I1 25348397 N/A physical interaction ComPPI
ECPAS DYNC1I1 25348397 N/A physical interaction ComPPI
DYNC1I1 STAU1 14525934 15121898 24234451 25348397 colocalization,association experimental interaction detection,physical interaction,imaging technique,tandem affinity purification ComPPI,HPRD,IntAct
DYNC1I1 RUNDC3B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DYNC1I1 FAM83D 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DYNC1I1 ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DYNC1I1 DYNC1LI2 25348397 N/A physical interaction ComPPI
DYNC1I1 SAMD1 25348397 N/A physical interaction ComPPI
DYNC1I1 MGA 25348397 N/A physical interaction ComPPI
DYNC1I1 BICD1 14525934 17139249 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection ComPPI,HPRD,IntAct
GSK3B DYNC1I1 14525934 17139249 N/A experimental interaction detection HPRD
H3-4 DYNC1I1 24234451 30021884 physical association cross-linking study IntAct

Visualization










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