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GENE：DYNC1LI1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DYNC1LI1
FullNmae dynein cytoplasmic 1 light intermediate chain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18745
EnsembleID ENSG00000144635
Uniprot Q9Y6G9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DYNC1LI1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DYNC1LI1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DYNC1LI1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DYNC1LI1 GO:0000226,GO:0000776,GO:0000922,GO:0003723,GO:0005515,GO:0005524,GO:0005813,GO:0005829,GO:0005868,GO:0005868,GO:0005874,GO:0005886,GO:0007018,GO:0007018,GO:0007049,GO:0016020,GO:0019003,GO:0030666,GO:0030667,GO:0045504,GO:0045504,GO:0051301,GO:0060090,GO:0060627,GO:0090267,GO:0101003

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DYNC1LI1 hsa:51143 path:hsa04145 Phagosome - Homo sapiens (human)
DYNC1LI1 hsa:51143 path:hsa04814 Motor proteins - Homo sapiens (human)
DYNC1LI1 hsa:51143 path:hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human)
DYNC1LI1 hsa:51143 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG DYNC1LI1 20026645 23180781 physical association far western blotting InnateDB
RAB11A DYNC1LI1 20026645 23180781 physical association far western blotting InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DYNC1LI1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DYNC1LI1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DYNC1LI1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 DYNC1LI1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 DYNC1LI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 DYNC1LI1 18668040 23622248 25416803 mrna cleavage,inhibition experimental interaction detection,clash TarBase
URS000076B539 DYNC1LI1 23313552 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001A4ABF DYNC1LI1 23313552 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 DYNC1LI1 23313552 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 DYNC1LI1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC5L DYNC1LI1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLL1 DYNC1LI1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB4A DYNC1LI1 11243854 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PSMC6 DYNC1LI1 25348397 N/A physical interaction ComPPI
TOMM22 DYNC1LI1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VCP DYNC1LI1 25348397 N/A physical interaction ComPPI
GABARAPL2 DYNC1LI1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DYNC1LI1 NUP85 10893222 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
DYNC1LI1 PCNT 25348397 N/A physical interaction ComPPI
DYNC1LI1 CUL3 25348397 N/A physical interaction ComPPI
DYNC1LI1 IKBKG 25348397 N/A physical interaction ComPPI
DYNC1LI1 DYNC1H1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNC1LI1 DYNC1LI2 25348397 N/A physical interaction ComPPI
DYNC1LI1 DYNLT1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNC1LI1 RANGAP1 25348397 N/A physical interaction ComPPI
DYNC1LI1 TXNRD1 25348397 N/A physical interaction ComPPI
DYNC1LI1 TKT 25348397 N/A physical interaction ComPPI
DYNC1LI1 ZFR 25348397 N/A physical interaction ComPPI
DYNC1LI1 DYNC1I2 25348397 N/A physical interaction ComPPI
DYNC1LI1 AKAP12 25348397 N/A physical interaction ComPPI
DYNC1LI1 DYNLRB1 25348397 N/A physical interaction ComPPI
DYNC1LI1 FLNA 25348397 N/A physical interaction ComPPI
DYNC1LI1 EIF3E 25348397 N/A physical interaction ComPPI
DYNC1LI1 HNRNPA0 25348397 N/A physical interaction ComPPI
DYNC1LI1 PSMD8 25348397 N/A physical interaction ComPPI
DYNC1LI1 RPS12 25348397 N/A physical interaction ComPPI
DYNC1LI1 SERBP1 25348397 N/A physical interaction ComPPI
DYNC1LI1 BICD2 25348397 N/A physical interaction ComPPI
DYNC1LI1 DCTN1 25348397 N/A physical interaction ComPPI
DYNC1LI1 DYNC1I1 25348397 N/A physical interaction ComPPI
DYNC1LI1 REL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DYNC1LI1 EGFR 25348397 N/A physical interaction ComPPI
DYNC1LI1 CLUH 25348397 N/A physical interaction ComPPI
DYNC1LI1 NUP214 25348397 N/A physical interaction ComPPI
DYNC1LI1 USP48 25348397 N/A physical interaction ComPPI
DYNC1LI1 XRCC6 25348397 N/A physical interaction ComPPI
DYNC1LI1 NTRK1 25348397 N/A physical interaction ComPPI
DYNC1LI1 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DYNC1LI1 NIN 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DYNC1LI1 BCOR 25348397 N/A physical interaction ComPPI
DYNC1LI1 POU5F1 25348397 N/A physical interaction ComPPI
DYNC1LI1 TRPT1 25348397 N/A physical interaction ComPPI
DYNC1LI1 C2CD2 25348397 N/A physical interaction ComPPI
DYNC1LI1 NFS1 25348397 N/A physical interaction ComPPI
DYNC1LI1 PAFAH1B1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNC1LI1 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DYNC1LI1 TRIM25 25348397 N/A physical interaction ComPPI
DYNC1LI1 MAD2L1 19229290 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation ComPPI,IntAct,OmniPath
DYNC1LI1 SOD2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DYNC1LI1 MAP1LC3B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DYNC1LI1 MYC 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
DYNC1LI1 TCTE1 24234451 25348397 26638075 association proximity-dependent biotin identification ComPPI,IntAct
DYNC1LI1 PGAM2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLT3 DYNC1LI1 25348397 N/A physical interaction ComPPI
DYNC1LI1 IKBKG 20026645 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009C3F62 DYNC1LI1 27087310 direct interaction,inhibition N/A NPInter

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