SEA - Browser View 1.2 version

Browser View of Super-Enhancers on Human Dec. 2013 (GRCh38/hg38) Assembly

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H3K27ac across cell-types/tissues

p300 across cell-types/tissues

BRD4 across cell-types/tissues

SE Constituent

DNA Methylation

Expression

TFBS by ChIP-seq

Conservation

conservation score

SpCas9 Target Site

Seed sequence for SpCas9 target site

SNP Site

disease snp (GWASdb)

disease snp (omim_snp)

4DGenome

"3C, 4C, 5C, ChIA-PET, Hi-C, Capture-C and IM-PET"

Med1 across cell-types/tissues

LNCaP

VCaP

Genomes

Genomes Selection

Human Dec. 2013
(GRCh38/hg38)
Mouse Dec. 2011
(GRCm38/mm10)
D. melanogaster Aug. 2014
(BDGP Release 6 + ISO1 MT/dm6)
C. elegans Oct. 2010
(WS220/ce10)
Zebrafish May 2017
(GRCz11/danRer11)
Chicken Dec 2015
(Gallus_gallus-5.0/galGal5)
Chimp May 2016
(Pan_tro 3.0/panTro5)
Rhesus Nov. 2015
(BCM Mmul_8.0.1/rheMac8)
Sheep Aug. 2012
(ISGC Oar_v3.1/oviAri3)
X.tropicalis Jul. 2016
(Xenopus_tropicalis_v9.1/xenTro9)
Stickleback Feb. 2006
(Broad/gasAcu1)

22Rv1	A549	A673
ACC112	Adipose	Adrenal Gland
adult dermal fibroblasts	AG04450	Aorta
ascending aorta	Astrocytes	bipolar spindle neuron
Bladder	BMP4 Mesendoderm Cells	BMP4 Trophoblast Cells
body of pancreas	Bone marrow derived macrophage	B cell
C4-2B	cardiac muscle cell	CD14-positive monocyte
CD25- CD45RO+ mem cells	CD25- IL17+ Th17 stim cells	CD25int CD127+ Tmem
CD3 Primary Cells	CD4+ CD25- CD45RA+ Naive Primary Cells	CD4 Primary Cells
CD56 Primary Cells	CD8 Primary Cells	coronary artery
Dnd41	DOHH2	epidermal keratinocytes
Esophagus	esophagus muscularis mucosa	esophagus squamous epithelium
Fetal Spinal Cord	gastrocnemius medialis	gastroesophageal sphincter
GM12878	GM23248	H1-hESC
H1 Neural Progenitor Cells	mesod_nodox_rep1	HiC_hESC
HCT-116	Heart Right Ventricle	HeLa-S3
hepatocyte	HepG2	HUES64 derived CD184+
IMR90	iPS-18a	iPS-20b
iPS 19.11	iPS DF 6.9	K562
Karpas-422	KMS-11	KOPT-K1
large intestine	Left Ventricle adult	Left Ventricle infant
Loucy	Lung	lung fibroblasts
mammary epithelial cells	MCF-7	Mesenchymal Stem Cells
MM.1S	Mobilized CD34 cells	muscle of leg
muscle of trunk	neural cell	neuroepithelial stem cell
neutrophil	OCI-LY1	OCI-LY3
osteoblast	ovary	Panc1
Pancreas	PC-3	PC-9
Peyers patch	placenta	Psoas Muscle
Right Atrium	right atrium auricular region	right lobe of liver
RWPE1	sigmoid colon	skeletal muscle myoblasts
skeletal muscle myotubes	Small Intestine adult	Small Intestine infant
smooth muscle cell	spleen adult	spleen infant
stomach	SUDHL6	thoracic aorta
Thymus	thyroid gland	tibial nerve
transverse colon	umbilical vein endothelial cells	upper lobe of left lung
uterus	vagina	VCaP

A549	breast epithelium	esophagus muscularis mucosa
gastroesophageal sphincter	GM12878	H1-hESC
HeLa-S3	HepG2	Ishikawa
K562	MCF-7	omental fat pad
osteoblast	ovary	prostate gland
sigmoid colon	SK-N-SH	stomach
subcutaneous adipose tissue	suprapubic skin	T47D
testis	tibial nerve	transverse colon
upper lobe of left lung	vagina

293 HEK	A375	Biphenotypic B Myelomonocytic Leukemia
LCLs	HAP1	HepG2
primary keratinocytes	K562	Kelly cells
Mammary gland adenocarcarcinoma epithelial cells	MDAMB231	MOLT4
MV-4-11-B	Primary B-CLL	prostate cancer
22Rv1	SK-MEL-5	SKmel147
ST1	U87 GBM

A0R_d0	Adrenal	Aorta
astrocyte of the spinal cord	NB	Bladder
T-cell	epidermal keratinocytes	Lymphoblastoid cells
HIC006	H1 hESC	H9
HIC001	Right Ventricle	HepG2
Hippocampus	HIC057	HIC050
K562	HIC069	Lung
etoh BS	H1 Mesenchymal stem cells	Ovary
Panc1	Pancreas	Psoas
RWPE1	SK-N-SH	Spleen
Thymus	HIC080

A549	Myers_AG04449_1_None_UW	CDI astrocytes
N1 [RRBS-seq]	CD3+ T-cell	Myers_GM12878_1_None_HudsonAlpha
HCT-116 parental (A)	Myers_HeLa-S3_2_None_HudsonAlpha	Myers_HepG2_1_None_Duke
Myers_K562_1_None_HudsonAlpha	NBE 1013140 DREAM	MCF-7
neutrophil	young set1_RRBS	Myers_PANC-1_2_None_HudsonAlpha
Myers_BC_Placenta_UHN00189_1_None_BioChain	Benign Prostate Tissue 1	WGBS from skeletal muscle myoblast
Myers_BC_Stomach_01-11002_1_None_BioChain	Myers_BC_Testis_N30_1_None_BioChain	Myers_BC_Uterus_BN0765_1_None_BioChain

A549-CEBPB	A549-Max	AG04450_CTCF
Dnd41_CTCF	Dnd41_EZH2	Gm12878-E2F4
Gm12878-IRF3	Gm12878-JunD	Gm12878-Max
Gm12878-NFKB	Gm12878-Nrf1	Gm12878-STAT3
Gm12878-USF2	Gm12878-YY1	Gm12878-EBF1_(SC-137065)
Gm12878-ELK1_(1277-1)	Gm12878-JunD	Gm12878-MafK_(ab50322)
Gm12878-NF-E2_(SC-22827)	Gm12878-NF-YA	Gm12878-NF-YB
Gm12878-RFX5_(200-401-194)	Gm12878-STAT1	H1-CEBPB
H1-JunD	H1-Max	H1-Nrf1
H1-USF2	H1-MafK_(ab50322)	H1-RFX5_(200-401-194)
H1-hESC_CTCFt	H1-hESC_MAX	H1-hESC_CEBPB
H1-hESC_CTCFb	H1-hESC_CTCFh	Hct-116-TCF7L2
HeLa-S3-CEBPB	HeLa-S3-E2F1	HeLa-S3-E2F4
HeLa-S3-E2F6	HeLa-S3-ELK1_(1277-1)	HeLa-S3-ELK4
HeLa-S3-IRF3	HeLa-S3-JunD	HeLa-S3-MafK_(ab50322)
HeLa-S3-Max	HeLa-S3-Max	HeLa-S3-NF-YA
HeLa-S3-NF-YB	HeLa-S3-Nrf1	HeLa-S3-PRDM1_(9115)
HeLa-S3-RFX5_(200-401-194)	HeLa-S3-STAT1	HeLa-S3-STAT3
HeLa-S3-TCF7L2	HeLa-S3-USF2	HepG2-Max
HepG2-Nrf1	HepG2-CEBPB	HepG2-CEBPB
HepG2-HNF4A	HepG2-IRF3	HepG2-JunD
HepG2-MafF_(M8194)	HepG2-MafK_(ab50322)	HepG2-MafK_(SC-477)
HepG2-RFX5_(200-401-194)	HepG2-TCF7L2	HepG2-USF2
Huvec-GATA-2	Huvec-Max	Imr90-CEBPB
Imr90-MafK_(ab50322)	Imr90-RFX5_(200-401-194)	K562-CEBPB
K562-E2F4	K562-E2F6	K562-ELK1_(1277-1)
K562-GATA-2	K562-IRF1	K562-IRF1
K562-IRF1	K562-IRF1	K562-JunD
K562-MafF_(M8194)	K562-MafK_(ab50322)	K562-Max
K562-Max	K562-NF-E2	K562-NF-YA
K562-NF-YB	K562-Nrf1	K562-RFX5_(200-401-194)
K562-STAT1	K562-STAT1	K562-STAT1
K562-STAT1	K562-STAT2	K562-STAT2
K562-USF2	K562-YY1	K562-ZNF263
Osteobl_CTCF	Panc1-TCF7L2	SK-N-SH_RA_CTCFh
SK-N-SH_RA_CTCFw	SK-N-SH_RA_EP300	SK-N-SH_RA_RAD21
SK-N-SH_RA_USF1	SK-N-SH_RA_YY1	T-47D+BPA_ESR1
T-47D+DMSO_CTCF	T-47D+DMSO_EP300	T-47D+DMSO_FOXA1
T-47D+DMSO_GATA3	T-47D+Estrad_ESR1	T-47D+Genist_ESR1