m6ADD overview
m6ADD is a database containing manually collected experimentally confirmed m6A-disease data and data obtained from high-throughput disease m6A modification profiles, aimed at exploring the association between m6A modified gene disorders and diseases. The m6ADD database contains 222 experimentally confirmed m6A-disease relationship pairs (human 185, mouse 37). We screened out differential m6A data from 30 sets of sequencing data of 16 diseases by two calculation methods, and provided a statistical evaluation result. The m6A-disease data includes m6A genomic location, disease name, m6A protein, regulatory mode, tissue / cell line, experimental method, and data source. In addition, we have developed a ppi network tool for obtaining differential m6A genes to show the function of these genes and a tool to predict m6A regulatory proteins associated with 24 types of cancers.
Currently, users can
Browse the experimentally supported and sequencing m6A-disease association data.
Search the experimentally supported and sequencing m6A-disease association data by particular keywords.
Download the experimentally supported and sequencing m6A-disease association data.
m6A-Net a ppi network tool for obtaining differential m6A genes.
m6A-Regulator a tool to predict m6A regulatory proteins for cancers.

 

 

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Contact us : zhangtyo@hit.edu.cn